It is the most common inherited blood disorder in the United States.
It affects about 100,000 children and adults in the U.S.
1 in 500 African American births
1 in 36,000 Latino births
Sickle cell disease is also common among people whose ancestors came from the Caribbean; Saudi Arabia; India; and Mediterranean countries
More than 100 million people worldwide have the genetic trait for sickle cell disease.
Complications can lead to diminished health-related quality of life, increased health care use and costs, and shortened lifespan.
There have been advances in sickle cell disease care, but disparities remain in the U.S.
Early study of the genetics of sickle cell disease spurred the development of the molecular medicine field. However these major contributions to modern medicine did not result in better clinical care for ALL people with sickle cell disease.
Vulnerability to infection;
Damage to vital organs including kidneys, lungs, brain;
Unpredictable pain episodes beginning in early childhood.